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Notable examples of ferroptosis inducers are erastin and RSL-3, which are widely recognized in the field

Inflammation and GLP-1s Chronic low-grade inflammation, also known as "inflammaging," is a common feature of many chronic diseases, including metabolic disorders, autoimmune conditions, and cardiovascular disease

Acceleration of GABA-switch after early life stress changes mouse prefrontal glutamatergic transmission

Ultimately, Compound 13 (DNS-0056) with pyran-methyl-pyridine and fluoro-methoxybenzyl substitutions at positions C-6/C-8 and C-9, respectively, emerged as the most potent derivative and was not a substrate of MDR1 (efflux ratio: 1.0) (Figure 5)