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Supported by an increasing number of studies these effects suggest the involvement of IGF-1 in metabolism coordination [136]
Retatrutide remains more research-focused in the published evidence base
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Room temperature allowances before use (single-dose devices): Wegovy: Up to 28 days at temperatures up to 86F (30C) Trulicity: Up to 14 days at temperatures up to 86F (30C) Mounjaro/Zepbound: Up to 21 days at temperatures up to 86F (30C) After first use (multi-dose pens only): Ozempic: Up to 56 days at room temperature or refrigerated Victoza/Saxenda: Up to 30 days at room temperature or refrigerated In warmer climates or during summer months, patients should be particularly cautious about leaving pens in hot cars, direct sunlight, or near heat sources
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