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It is an important concept in pharmacology, as it helps to determine the dosage and frequency of drug administration
Collectively, these findings suggest that nose-to-brain delivery of L-penetratin/insulin was effective in the early stage of cognitive dysfunction and that nasal administration of L-penetratin/exendin-4 with insulin boosted therapeutic effect of exendin-4 in the progressive memory dysfunction in vivo
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We recommend to start with 4 sessions one week apart each, and then once a month, but a healthcare professional will determine an appropriate schedule, which may include regular intervals
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