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10.3389/fnagi.2024.1417515 54

By resolving cellular heterogeneity and integrating different layers of molecular information, these approaches can provide unprecedented insights into the mechanisms driving vascular dysfunction and identify novel therapeutic strategies (Fig

Heme is a potent inflammatory molecule that activates the innate immune system and endothelial cells, leading to an inflammatory and pro-adhesive state (Wagener et al., 2001)