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16,18 Some studies also suggest that mebendazole is less likely to cause oxidative stress than some other benzimidazoles such as albendazole
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173 At the molecular level, gene modulation techniques, including siRNA- and shRNA-mediated silencing of efflux transporter genes (e.g., ABCB1, ABCG2), as well as CRISPR/Cas9-based gene editing, have successfully resensitized tumor cells to chemotherapy in preclinical models
The hemolysis rate was calculated as follows: Cytotoxicity study RAW 264.7 cells were seeded into 96-well plates at a density of 1 10 4 cells per well and incubated at 37 C with 5% CO 2 in DMEM supplemented with 10% FBS for 12 h
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