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Wegovy (semaglutide) and Wellbutrin (bupropion) are two distinct medications with different clinical indications, though patients may occasionally be prescribed both concurrently

Moreover, they show that metformin enhances the expression of the genes encoding the receptors for both GLP-1 and glucose-dependent insulinotropic polypeptide (GIP) in mouse islets and also increases the effects of GIP and GLP-1 on insulin secretion from beta cells

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Alongside that popularity has come wide-ranging reports of side effects from users, including nausea, dry mouth, and constipation