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These included: Anencephaly (underdeveloped brain and/or incomplete skull) Cleft palate Gastroschisis (a hole in the abdominal wall through which intestines or other abdominal organs may protrude) Narrowing of the aorta and other heart defects The study hypothesizes that birth defects caused by venlafaxine could result from the drug interfering with embryologic signaling pathways that rely on serotonin and norepinephrine

Second, several experiments whether they involve slices of brain tissue, animals, and even human volunteers have strongly suggested that GLP-1 drugs specifically act on our dopamine cycles and affect neural activity in the hypothalamus, the appetite-controlling region of the brain

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