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As these dosing schedules are recommended off-label, no clinical trials have been conducted on biweekly dosing of semaglutide, and long-term safety remains unknown
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The drug now carries a warning for severe pancreatitis and severe kidney injuries
Ferroptosis is usually caused by the oxidative stress damage induced by iron overload, which exceeds the antioxidant capacity
Given the experimental evidence mentioned above, investigating new proeryptotic and antieryptotic molecules is essential for expanding our understanding of the cellular mechanisms underlying the programmed death of erythrocytes and for opening new avenues in the study of pathologies associated with eryptosis
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