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Topical human skin trials: a small number of double-blind RCTs (best example: Leyden et al., published in the 1990s and 2000s) showing modest improvements in skin laxity, fine lines, and surface density

By binding to GLP-1 receptors in the brain, pancreas, and gastrointestinal tract, Wegovy produces several therapeutic effects: it enhances insulin secretion in a glucose-dependent manner, suppresses glucagon release, slows gastric emptying, and reduces appetite through central nervous system pathways that regulate satiety

You can think of oxidative stress as "biological rust" that can wear down your cellular health over time

The aim of this study was to determine clinical, radiological, and manometric outcomes at 34 months after DVSS in this treated IIH cohort