Clinical use and practical aspects Patients who need further intensification of therapy but have had it delayed because of concerns about potential weight gain and hypoglycemic episodes would probably benefit from fixed-ratio combination of basal insulin and GLP-1Ras [19, 22, 23, 25,26,27, 30, 31]

Access this article Similar content being viewed by others Abbreviations ASL: Argininosuccinic acid lyase ASS: Argininosuccinate synthetase ATP: Adenosine 5-triphosphate BBB: Blood-brain barrier BCAA: Branch chain amino acids CPS: Carbamyl phosphate synthetase CT: Computed tomography GI: Gastrointestinal ICH: Intracranial hemorrhage IEM: Inborn error of metabolism IV: Intravenous LOLA: L-Ornithine-L-aspartate MRI: Magnetic resonance imaging NAGS: N-Acetyl glutamine synthetase OTC: Ornithine transcarbamylase RRT: Renal replacement therapy TPN: Total parenteral nutrition UCDs: Urea cycle disorders US: Ultrasonography References Papers of particular interest, published recently, have been highlighted as: Of importance Of major Importance Bachmann C
Presented for research literature review only Fukai F et al
Balkesir Salk Bilimleri Dergisi 11(2):167172 Tipu M, Saleem U, Rehman T, Aslam M, Muhammad K, Hussain K, Bukhari N, Hassan S, Hussain Z, Faisal M (2015) Protective role of lactobacillus acidophilus against aflatoxin b1-induced immunosuppression