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Those findings cannot predict when, or whether, a person would notice a result
The absence of published half-life data is a direct consequence of how early this compound is in development: it has been used as a research tool to validate an enzyme target, not as a clinical candidate with a full pharmacokinetic package
"Obesity drugs in clinical development." Current Opinion in Investigational Drugs 7.4 (2006): 312
Niacinamide (B), like niacin, has several notable interactions
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