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Because AMY receptors also interact with calcitonin, dual amylin/calcitonin receptor agonists (DACRAs) have been developed, with preclinical studies finding greater weight loss than with amylin analogues alone, and additional efficacy in combination with a GLP-1RA [70]
Side Effects and Tolerability Comparison Both tirzepatide and semaglutide share common side effects including nausea, vomiting, constipation, and diarrhea, particularly during the first few weeks of treatment
The tissues homoge- nates were precipitated with trichloroacetic acid
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