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GLP-1 RAs exert an antihyperglycemic effect by enhancing pancreatic -cellmediated glucose-dependent insulin secretion, suppressing glucagon secretion, delaying gastric emptying, and reducing food intake in patients with T2D [6]
For example, the upregulation of the Nrf2 pathway by lipoic acid in cultured hepatocytes and in the liver of obese or diabetic rats prevented lipid overload-induced steatosis (35) and cell death (36)
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