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Sin embargo, otros ensayos aleatorios controlados no han encontrado ningn beneficio del tratamiento con citicolina en el tratamiento del accidente cerebrovascular isqumico agudo (98, 99), incluido un ensayo reciente que evalu sus efectos cuando se administra inmediatamente despus de la trombectoma endovascular (es decir, terapia de recanalizacin) y se contina durante 42 das (100)

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