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9 Rather than functioning as a stand-alone approach, glutathione is more commonly considered as one variable within complex mood and inflammatory profiles, especially when oxidative stress or low-grade inflammation appears to contribute to the overall clinical picture

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Song et al showed that decreasing periplasmic GSH by deleting the GSH exporter CydD triggers the CpxR/SoxS two-component systems, upregulating the AcrAB-TolC pump and lowering intracellular drug accumulation