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CuiWZhangWYuanXLiuSLiMNiuJet al

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A large mutagenesis study identified key residues in the GLP-1R surface region which either interact with the ligand or assist with propagation of occupancy to the cytosol 20

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Oral tablets currently hold the balance

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Some of the reabsorbed K + is effluxed back into the lumen through the action of the KCNJ1 encoded potassium channel more commonly called ROMK (renal outer medullary potassium channel)

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