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Pharmacological Research, Volume 222, 2025
For storage and handling, Dihexa should be stored as a lyophilized powder at -20C, where it is stable for 24+ months
Importantly, in one study, nearly three-quarters of participants with prediabetes returned to normal blood sugar levels, suggesting that retatrutide may help not only manage but even reverse early metabolic dysfunction
It is contraindicated in patients with certain mitochondrial disorders, porphyria, or fatty acid oxidation deficits
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