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The oxidative phase of the pathway begins with glucose-6-phosphate, which is the product of the hexokinase reaction initiating glycolysis (Figure 1)
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Some of these medications include: fluphenazine (Prolixin) magnesium salicylate (Novasal) mexiletine (Mexitil) salsalate There is some concern that high-dose vitamin C might make radiation therapy and some chemotherapy drugs less effective
High-dose intraperitoneal N-acetylcysteine (800 mg/kg) induced acute liver, kidney, and spleen damage in mice, leading to mortality
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