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[3] Tirzepatide is administered once weekly via subcutaneous injection and works by enhancing insulin secretion in response to meals, suppressing glucagon release, slowing gastric emptying, and reducing appetitemechanisms that collectively improve glycaemic control and promote weight loss
This deficiency may contribute to the oxidative stress and inflammation commonly observed in lupus patients
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Clinical studies have raised concerns regarding reductions in lean body mass during GLP-1RA therapy [40], whereas preclinical studies report improvements in muscle mass and strength [41,42,43]
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