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View Study [3]"IGF-I and IGFBP-3 transport in the rat heart" Boes M, Dake BL, et al., 2003 Finding: This study showed that LR3 IGF-I can bypass IGF binding proteins that normally sequester IGF-1, demonstrating why LR3 has greater bioactivityit reaches target tissues more effectively than native IGF-1
The key implication here is that FOXO4-DRI has the potential to develop supportive care protocols to reduce long-term adverse effects of chemotherapy and improve overall quality of life for cancer survivors
Biochimica et Biophysica Acta, 1852 (6), 1209-1218
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