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Age is often the biggest factor because skin loses elasticity as the years pass
Hyaluronic acid is a natural substance found in the skin that helps retain moisture and elasticity
Naturally occurring copper tripeptide that activates fibroblasts to upregulate collagen I/III/IV and elastin synthesis, inhibits MMP-1/2/9 collagen degradation enzymes, activates lysyl oxidase for collagen cross-linking, stimulates wound bed angiogenesis via VEGF/FGF-2, and activates Nrf2 antioxidant response element genes
Pharmacological alleviation of oxidative stress effectively ameliorates DR pathology, validating oxidative damage clearance as a promising therapeutic strategy for DR
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