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Up-regulation of nicotinamide phosphoribosyltransferase and increase of NAD + levels by glucose restriction extend replicative lifespan of human fibroblast Hs68 cells
In a 2015 review in BioMed Research International , Pickart, Vasquez-Soltero and Margolina collated Connectivity Map data showing GHK modulates expression of roughly 31 percent of profiled human genes in cultured fibroblasts
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