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These can include digestive discomfort such as bloating or stomach cramps, and in rare cases, allergic responses like skin rashes or itching
In another study, published in Clinical Pharmacokinetics , researchers also found that water intake, fasting time and meal timing can affect the amount of the drug that enters the bloodstream
This approval was based on the SURPASS clinical trial program, which demonstrated superior glycemic control compared to placebo, semaglutide 1 mg, and insulin degludec across multiple studies
10.1111/jnc.12469 322
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