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Wang J, Gallagher D, Devito LM et al (2012) Metformin activates an atypical PKC-CBP pathway to promote neurogenesis and enhance spatial memory formation
Peters S, Stahel R, Bubendorf L, Bonomi P, Villegas A, Kowalski DM, et al
It also plays a protective role in cardiovascular health, as it helps to reduce excess amounts of a protein called homocysteine which, at high levels, is inflammatory
By blocking NNMT, it shifts intracellular NAD+ and S-adenosylmethionine (SAM) levels, two cofactors tied to energy metabolism, redox balance, and gene regulation in laboratory models
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