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However, given the associated risks of cardiovascular disease and various cancers, the benefits of these medications, such as better glycemic control, weight loss and improvement in cardiometabolic risk factors as well as other obesity complications, appear to outweigh the risks for most adults with obesity [143, 153]

The article says berberine may be appropriate for prediabetic patients with mildly elevated fasting glucose or an A1C of 5.7 to 6.4 percent, as an adjunct to lifestyle interventions

By distribution channel, the retail pharmacies segment held a dominant position in the GLP-1 market, with a 54% share in 2025

Basic Res Cardiol (2015) 110:6