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In HCC driven by obesity and nonalcoholic steatohepatitis, the downregulation of CPT2 leads to the accumulation of acylcarnitines, among which C18:1-carnitine enhances spheroid formation by HCC cells through STAT3 activation, indicating that the accumulation of acylcarnitine can promote the development of liver cancer [212]
The hypothalamus is the starting point in thyroid hormone regulation
637,638 Compared with physiological aerobic oxidation, glycolytic alterations in tumor cells promote crucial biological processes such as proliferation, stemness, and metastasis
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