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Panel B shows the GSH regulatory motif (taken from Figure 1), including the effects of estradiol and the inhibition of GCL and glutathione synthetase (GS) by GSH
These effects may be related to Saxenda-induced dehydration
At Centra Internal Medicine, we follow evidence-based guidelines that recommend patients continue tirzepatide as long as they are experiencing benefitssuch as ongoing weight loss or improved overall metabolic healthand are not experiencing intolerable side effects
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