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The original branded metformin was known as Glucophage
a single missed dose rarely causes dramatic weight gain, but reduced appetite control over several days can lead to a 13 pound increase, often from water retention and increased food volume rather than new fat gain
.,BermanoG,ArthurJRHeskethJESelective control of cytosolic glutathione peroxidase and phospholipid hydroperoxide glutathione peroxidase mRNA stability by selenium supply.1996;387(2-3):157160 70
For people with type 2 diabetes who are also taking insulin or sulfonylureas, there is an increased risk of hypoglycaemia (low blood sugar)
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