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This could explain why tirzepatide (which stimulates the GIP pathway in addition to GLP -1) can be administered at higher doses than semaglutide (which only stimulates GLP-1), without amplifying the side effects typical of GLP-1 agonists (nausea, vomiting)
It can be a good fit for adults with obesity (BMI 30 and over) overweight adults (BMI over 27) with a weight-related issue like high blood pressure or cholesterol those with type 2 diabetes Its probably not a good fit for women who are pregnant, trying to get pregnant, or breastfeeding, since theres not enough safety data people with type 1 diabetes people with pancreatitis or a history of medullary thyroid cancer True Stories Of Transformation What Is Retatrutide
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