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The result, in the landmark STEP clinical trials published in The New England Journal of Medicine , was an average body weight reduction of approximately 15% over 68 weeks a level of efficacy previously only seen with bariatric surgery

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These are non-coded amino acids, meaning they do not appear naturally in human proteins

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Identifying these patients early enables clinicians to tailor therapies that not only address glucose but also hepatic risk, making treatment with GLP1 therapies more impactful

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