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Medical Evaluation Rule Out Key Risks Your physician must first rule out serious pre-existing conditions where GLP-1 analogues are contraindicated: History of pancreatitis Medullary thyroid carcinoma (MTC) or family history of MEN-2 (contraindicated) Severe gastrointestinal disease (gastroparesis, severe reflux) Significant renal impairment (dose adjustment/avoid in severe CKD) Baseline labs: fasting glucose, HbA1c, renal & liver function

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