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Research models frequently examine GHKCus role in metalion transport , ECMassociated signaling , redoxbalance pathways , and cellularresponse mechanisms , making it a widely studied tool in metallopeptide and oxidativestress research
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We begin by delineating intrinsic and acquired resistance pathways, including alterations in drug transport and metabolism, signaling rewiring, epigenetic remodeling, the DNA damage response, and tumor microenvironmental adaptation
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