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For intramuscular and intravenous administration
The prespecified selection criteria included: (1) RCTs reporting desired cardiovascular or renal outcomes
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Another potential therapeutic, Minocycline is a microglial inhibitor which reduces BBB dysfunction by preventing production of glutamate, matrix metalloproteinases, and the proinflammatory cytokine, IL-1, and increasing the levels of cells responsible for the remyelination of neurons which would be relevant in treating AD [138, 140,141,142]
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