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Although the direction of association was consistent and statistical heterogeneity was low, serious concerns about indirectness arose because NAION diagnoses were based on administrative coding without ophthalmologic confirmation, and key risk modifiers (optic disc anatomy, rate of glycemic reduction) were not accounted for
GLP-1s are typically prescribed to help manage Type 2 diabetes and weight
Increased nitric oxide activity has also been demonstrated in resistance trained persons with reactive hyperaemia testing, an assessment used in clinical settings that, to some degree, simulates the physical stresses encountered during very intense exercise such as resistance training [7]
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