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However, excessive alcohol consumption can impair absorption by damaging the gastric mucosa and reducing intrinsic factor production essential for B12 uptake

If you tend to have digestive problems, a B12 deficiency can make them worse

If a pregnant patient has a documented deficiency of one or more B vitamins or a condition like hyperemesis that prevents oral intake, the benefits of correcting the deficiency (preventing serious maternal and fetal complications) outweigh any minimal risk from the injection

NAD+ must be administered with a separate syringe and at a different site because its acidic solution can degrade the KLOW peptides on contact