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Interestingly enough, the in vivo kidney switches fuels from lactate to glutamine oxidation in metabolic acidosis[31] so that the anaplerotic glutaminolysis-GDH reactions matches [32] the cataplerotic reactions(CO 2 , biomass formation, [30,31] as does acid excretion (2NH 4 + /glutamine) and base(2HCO 3 - /glutamine) generation
Jetzt, da wir dies wissen, ist es jedoch mglich, nach Inhibitoren der Enzyme im Desaminierungsweg zu suchen, die in unserer Studie identifiziert wurden, hofft die Mikrobiologin.
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