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Moreover, liraglutide elicited a phenotypic shift in macrophages from proinflammatory M1 to anti-inflammatory M2, while also inhibiting the expression of enzymes implicated in cartilage degradation

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Cannabis has complex gastrointestinal effectswhilst some patients use it to manage nausea, chronic heavy use is associated with cannabinoid hyperemesis syndrome (CHS) , characterised by severe cyclical vomiting