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FEBS Lett 480: 193196
Effects of Roux-en-Y gastric bypass on energy and glucose homeostasis are preserved in two mouse models of functional glucagon-like peptide-1 deficiency
This survival mechanism prioritises essential functions like heart and brain activity while reducing energy available for physical activity and alertness
Overall, these results indicate that SKN-1 is activated in all three sterile mutants and appears to be a key regulator of their lifespan, but is not the factor that accounts for their differential lifespan
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