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Lastly, although many of the beneficial effects attributed to GLP-1 RAs are inferred from established molecular pathways or disease surrogates, it is essential to distinguish between weight-lossmediated and weight-independent geroscience effects
These agents mimic the action of glucagon-like peptide-1, stimulating insulin secretion, slowing gastric emptying, and promoting satiety
Third, we restricted the study outcome to histologically verified prostate cancer to increase the specificity of the case definition
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