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The individual ages ranged from 29 to 100 years (mean age, 65.2 17.8), and the mean age of males and that of females was 64.7 15.7 and 66.2 21.7 years, respectively

An editorial appearing in the Journal of the American Medical Association in 2020 really hit home by saying it's time that we focus on the metabolic issues related to Alzheimer's disease and back down on this whole notion that it's caused by the accumulation of beta-amyloid

This mutation leads to detrimental phenotypes such as premature aging, senescence, immune deficiency, and neurodegeneration 111,288

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