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These medications work by mimicking the action of the naturally occurring GLP-1 hormone, which stimulates insulin secretion in a glucose-dependent manner, suppresses glucagon release, slows gastric emptying, and promotes satiety
This combination provides significant GH elevation without appetite stimulation, cortisol elevation, or prolactin increases
USE IN PATIENTS WITH HEPATIC IMPAIRMENT One clinical trial has been published assessing the safety, tolerability, and pharmacokinetics of oral semaglutide in patients with hepatic impairment
Mechanism of action: Mounjaro works by mimicking the naturally occurring gut hormones GLP-1 and GIP (sometimes also called gastric inhibitory polypeptide)
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