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Nitrates in spinach function as nitric acid donors which induce a vasodilating effect in the arteries and veins, due to relaxation of endothelial smooth muscle which can reduce the risk and/or severity of stable effort angina, acute cardiac insufficiency, and acute coronary syndrome
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Such models are used to evaluate signaling interactions, biomarker expression, and structural organization under controlled laboratory conditions, with emphasis on reproducibility and mechanistic interpretation rather than applied outcomes
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