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Furthermore, the potential for this therapeutically desirable property was not suggested from the measurement of acute cAMP responses in CHO-GLP-1R cells, a standard in vitro metric for GLP-1R agonist performance in drug development 23 , where the more insulinotropic compounds displayed reduced potency vs
Frias JP, Bastyr EJ 3rd, Vignati L et al (2017) The sustained effects of a dual GIP/GLP-1 receptor agonist, NNC0090-2746, in patients with type 2 diabetes
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