They received instructions to swallow it three times a day ( three capsules of 1 g each), after main meals, recording daily the quantity of capsules ingested on a specific form named Participants daily card. For each return visit to the site of research, aiming to receive, the participants answered to an adherence form, filled out by the pharmacist, immediately after medical appointment
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These include naturally DPP-4 resistant GLP-1 analogs (e.g., exendin-4)
The PA criteria require BMI 30 or higher (or 27 with a comorbidity such as type 2 diabetes, hypertension, dyslipidemia, OSA, or CVD), documentation of a 6-month structured weight management program, prescriber attestation that lifestyle change alone has failed, and age 18 or older