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In SURMOUNT-1, 3.2% of tirzepatide patients reported injection-site reactions, which were mostly erythema and pruritus at the injection site [1]
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In a Phase 2 trial published in the New England Journal of Medicine in 2023, participants taking the highest dose of retatrutide lost an average of 24.2 percent of their body weight over 48 weeks
Sticova E, Jirsa M
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