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In addition, we have observed increased neuronal activation in the LH upon OB GLP-1R stimulation and the existence of an anatomical connection between the AON and LH
Restrictive eating patterns inherently low in a variety of fiber, resistant starches, and polyphenol-rich foods diminish substrates required for diverse gut bacterial populations and adequate microbiome diversity
Gastrointestinal symptoms top the list
It is also a primary site of drug detoxification, which relies heavily on GSH availability 28
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