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The muscle is injected with the medication (known as an intramuscular injection)
It is reported that high concentrations of fumarate and succinate can enhance the 3-methylation of histones H3K4 and H3K27 by inhibiting KDM5 histone demethylase (responsible for H3K4 demethylation) and JMJD3 histone demethylase, respectively, which in turn promotes the expression of pro-inflammatory cytokine genes (115, 125, 161, 162)
The market is expected to grow from $43,904 million in 2025 at a compound annual growth rate (CAGR) of 13%
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