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GHK-Cu has the longest human safety record through decades of cosmetic use, with no significant systemic adverse events reported in topical applications 34
This may be attributed to its overall positive effects on cell functions, energy metabolism, and neurotransmission
Exp Physiol 108:1227 Badenoch JB, Rengasamy ER, Watson C, Jansen K, Chakraborty S, Sundaram RD, Hafeez D, Burchill E, Saini A, Thomas L, Cross B, Hunt CK, Conti I, Ralovska S, Hussain Z, Butler M, Pollak TA, Koychev I, Michael BD, Holling H, Nicholson TR, Rogers JP, Rooney AG (2022) Persistent neuropsychiatric symptoms after Covid-19: a systematic review and meta-analysis
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