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All statistical analyses, except for the calculation of the integrated OR for the primary outcome, were performed using the IBM SPSS Statistics software (version 28.0
The International Council for Harmonisation (ICH) has developed guidelines applicable to peptide therapeutics, reducing duplicative requirements across regulatory jurisdictions
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A study indicates that 6% to 15% of opioid-nave post-op patients became chronic opioid users after major or minor surgery, including 4% of those who underwent total hip arthroplasty and 8% of total knee arthroplasty
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