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Efficacy and safety of once-weekly dulaglutide in combination with sulphonylurea and/or biguanide compared with once-daily insulin glargine in Japanese patients with type 2 diabetes: a randomized, open-label, phase III, non-inferiority study

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You might think that would at least coincide with a superior safety profile, but that same study saw a greater rate of trial discontinuation due to adverse effects in the liraglutide group than in the semaglutide group.7 It also requires daily dosing, which is less convenient than the weekly administration of semaglutide and tirzepatide

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